Generic Glucophage Sr (Metformin 500/1000mg)

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What is/are Glucophage Tablets?

METFORMIN is used to treat type 2 diabetes. It helps to control blood sugar. Treatment is combined with diet and exercise. This medicine can be used alone or with other medicines for diabetes, including insulin. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

Glucophage is a biguanide antidiabetic. It works by decreasing the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce.

Sustained-release (SR), extended-release (ER, XR, or XL), time-release or timed-release, controlled-release (CR), or continuous-release (CR or Contin) pills are tablets or capsules formulated to dissolve slowly and release a drug over time. The advantages of sustained-release tablets or capsules are that they can often be taken less frequently than instant-release formulations of the same drug, and that they keep steadier levels of the drug in the bloodstream.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

• anemia
• frequently drink alcohol-containing beverages
• become easily dehydrated
• heart attack
• heart failure that is treated with medications
• kidney or liver disease
• severe infection
• severe dehydration
• low blood oxygen levels
• high blood ketone or acid levels
• polycystic ovary syndrome
• serious infection or injury
• vomiting
• an unusual or allergic reaction to metformin, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant, breast-feeding

How should I use this medicine?

Take this medicine by mouth. Take it with meals. Swallow the tablets with a drink of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 10 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose of, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

What may interact with this medicine?

Do not take this medicine with any of the following:

• dofetilide
• gatifloxacin
• certain contrast medicines given before X-rays, CT scans, MRI, or other procedures

This medicine may also interact with the following:

• cimetidine
• digoxin
• amiloride
• calcium channel blockers
• sulfonylureas
• sympathomimetics
• diuretics like amiloride, furosemide
• female hormones, like estrogens or progestins and birth control pills
• isoniazid
• medicines for blood pressure like nifedipine
• morphine
• nicotinic acid
• phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine
• phenytoin
• procainamide
• quinidine
• quinine
• ranitidine
• steroid medicines like prednisone or cortisone
• stimulant medicines for attention disorders, weight loss, or to stay awake
• trimethoprim
• thyroid medicines
• vancomycin

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

• allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
• breathing problems
• dizziness or lightheadedness
• fast or difficult breathing
• feeling of being unusually cold
• low blood sugar (ask your doctor or health care professional for a list of these symptoms)
• muscle aches or pains
• slow or irregular heartbeat
• unusual stomach pain or discomfort
• unusual drowsiness
• unusually tired or weak

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

• diarrhea
• headache
• gas
• indigestion
• heartburn
• temporary metallic taste
• vomiting
• nausea
• stomach upset

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress.

Learn how to check your blood sugar. Learn the symptoms of low and high blood sugar and how to manage them.

If you have low blood sugar, eat or drink something that has sugar. Make sure others know to get medical help quickly if you have serious symptoms of low blood sugar, like if you become unconscious or have a seizure.

Glucophage may rarely cause a serious and sometimes fatal condition called lactic acidosis. Most of these cases have occurred in diabetic patients who also have certain kidney problems. The risk of lactic acidosis may be greater if you have liver problems, kidney problems, or heart failure. The risk may also be greater in patients who are elderly or drink alcohol.

Do not begin to take Glucophage if you are older than 80 years old unless lab tests show that you do not have decreased kidney function. Do not take it if you have a severe infection, have low blood oxygen levels, or are dehydrated. Tell your doctor you take Glucophage before you have any surgery or lab procedures.

If you need surgery or if you will need a procedure with contrast drugs, tell your doctor or health care professional that you are taking this medicine.

Wear a medical identification bracelet or chain to say you have diabetes, and carry a card that lists all your medications.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture and light. Throw away any unused medicine after the expiration date.

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